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What Is Lipase In Blood Test

by Annabel Caldwell
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What Is Lipase In Blood Test

What Is Lipase In Blood Test

Lipase is a type of protein made by your pancreas, an organ located near your stomach. Lipase helps your body digest fats. It’s normal to have a small amount of lipase in your blood. But, a high level of lipase can mean you have pancreatitis, an inflammation of the pancreas, or another type of pancreas disease.

While it might seem like there are more than enough tests out there for testing your thyroid, kidney function and cholesterol levels, there aren’t many that test specifically for Pancreatic Lipase (PL) as one of their parameters. The following article will explore what PL is, how it works with your digestive system and why having too much of it could be dangerous.
Pancreatic Lipase is a type of enzyme produced by your pancreas which aids your digestion and absorption of fat. Pancreatic lipase breaks down triglycerides into fatty acids and monoglycerides. This process allows your body to absorb these fatty acids into your bloodstream so they can be used throughout your body. Without this enzyme, your body would not be able to properly utilize all those tasty fats and carbohydrates from foods such as steak and ice cream. Your digestive tract uses enzymes to break down food into smaller components before being absorbed through the walls of your intestines. These enzymes come in different forms; some work on carbohydrates while others work on proteins. Pancreatic lipase is the main enzyme responsible for breaking down fats.
Pancreatic lipase also plays an important role in the production of energy within our bodies. When we eat carbohydrates, glucose molecules begin combining together in order to create energy. Glucose molecules combine together using a chemical reaction that releases heat called glycolysis. Once the glucose has been broken apart and converted into energy, lipids are transported across cell membranes via specific carriers. The carrier proteins involved in transporting lipids include CD36, FAT/CD36, HLADR and GPIHBP1. As mentioned above, lipases help transport lipids across cell membranes, allowing them to be recognized by other cells that need them. Pancreatic lipase attaches itself to these carriers, which transports the lipid directly into the appropriate area where it can be utilized for cellular energy.
In addition to helping your body use fat for energy, pancreatic lipase also has an indirect effect on insulin sensitivity. Because lipids are essential building blocks for healthy skin and nerves, they play an important role in maintaining overall health. Insulin is primarily responsible for controlling the balance between sugar supply and demand inside your body. However, without proper functioning pancreatic lipase, your body may become overly sensitive to insulin, leading to diabetes.
A number of diseases can affect the activity of lipases in the human body. One common condition is known as hyperlipoproteinemia. People who suffer from this genetic disorder have abnormally low amounts of HDL (“good”) cholesterol floating around in their blood stream. Since lipases are necessary to break down both LDL (“bad”) cholesterol and HDL cholesterol, people suffering from hyperlipoproteinemia often experience problems with the metabolism of lipids because of their decreased levels of pancreatic lipase. Other disorders that lower the amount of lipase circulating in the blood include:
– Pancreatitis: An infection of the pancreas, pancreatitis causes damage to the pancreas’ tissue, thereby decreasing its ability to produce lipase. Inflammation caused by pancreatitis damages the lining of the pancreas, causing it to malfunction and stop producing lipase needed to metabolize fats.
– Bile duct obstruction: A blockage in the bile ducts prevents pancreatic lipase from moving into the intestine to prepare nutrients for absorption. Patients with this problem often experience abdominal pain, jaundice and weight loss.
– Autoimmune hepatitis: A buildup of immune complexes destroys liver cells, preventing the liver from producing large quantities of pancreatic lipase.
– Hyperthyroidism: Thyroid hormone increases the size of thyrocytes, which makes them release more lipase into the blood stream. This excess lipase then travels through the blood to the liver, where it is destroyed.
– Cirrhosis of the liver: Liver failure decreases the ability of the liver to filter toxins and waste products from the blood. With less filtering provided by the liver, toxins build up in the blood, eventually damaging the liver. Decreased levels of lipase allow toxic substances to accumulate in the blood, reducing the body’s ability to metabolize harmful chemicals.
– Cancerous tumors: Tumors growing in areas such as the ovaries or kidneys prevent the pancreas from releasing sufficient levels of lipase.
As you can see, lipases do an amazing job of ensuring the right combination of nutrients get delivered to the correct places at the right time. They’re so important that if they were suddenly missing from the equation, it could result in serious complications. Therefore, it’s always best to keep yourself well informed about any changes to your diet, exercise routine and lifestyle habits. If you suspect you or someone you love suffers from pancreatitis, consult your doctor immediately. For more information on Pancreatic Lipase and related topics, check out the links below.

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1 comment

graliontorile May 16, 2022 - 1:34 am

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